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KMID : 1134820100390121800
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Journal of the Korean Society of Food Science and Nutrition
2010 Volume.39 No. 12 p.1800 ~ p.1806
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Effects of Vanadium Water on Cancer-related Fatigue of Non Advanced Cancer Patients : Randomized Double Blinded Controlled Trial
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Zheng Hong-mei
Kim Dong-Hee
Lee Suk-Hoon
Park Yoo-Kyoung
Yoo Hwa-Seung
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Abstract
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This study was conducted to evaluate the efficacy and safety of vanadium water (VW) on cancer-related fatigue of non-advanced cancer patients. For the experimental group administration, participants consumed three 500 mL/bottle bottles of Jeju Island’s VW, which contained 15～20 ppb of vanadium, three times a day (morning, afternoon, evening) for 4 weeks (28 days) without any additional treatments for fatigue improvement. The control group participants consumed three 500 mL/bottle bottles of ordinary water (0 ppb of vanadium) three times a day for the same period of time without any additional treatments for fatigue improvement. After 4 weeks of VW consumption, total score of Revised Piper Fatigue Scale (RPFS) was reduced 30% compared to the basal score after Fisher’s Exact Test which resulted in a statistical borderline significance (p=0.0799) and result of t-test of comparison between two groups’ RPFS total score and fatigue cognitive/mood changes resulted in a statistical significance (p=0.0112). In detail, only 36.4% of control group (N=11) showed improvement while 77.8% of treatment group (N=9) showed fatigue improvement. No other lab measures, including thyroid hormone level indicated any significant differences between two groups. In conclusion, daily consumption of 1.5 L of vanadium water for 4 weeks showed improvement of non-advanced cancer patients’ fatigue.
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KEYWORD
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cancer-related fatigue, vanadium water, revised piper fatigue scale, randomized controlled trial
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